Parkinson's disease is a progressive neurodegenerative brain disease (loss of brain cells). So what does that mean? Parkinson's patients will continue to live with this disease for 20 years or more after being diagnosed. However, this does not mean that there will be no change in quality of life with this disease. Because there is no treatment for the complete elimination or prevention of the disease, doctors who treat you are currently focused on treatments for controlling the symptoms of Parkinson's disease.
Normally there are brain cells (neurons) that produce dopamine in certain regions of the human brain. These cells are concentrated in a certain area of the brain called substabynia nigra. Dopamine is a chemical that transmits messages between the substantia nigra and other brain regions that control body movements. Dopamine allows people to perform fluent and coordinated movements. When 60% to 80% of dopamine-producing cells are lost, a sufficient amount of dopamine cannot be produced and motor symptoms of Parkinson's disease occur. This process of deficiency in brain cells is called neurodegeneration. According to the existing theory, the earliest symptoms of Parkinson's disease occur in the enteric nervous system, lower brain stem and odor tracts. According to this theory, Parkinson's disease spreads from these regions to the upper parts of the brain, that is, substanisia nigra and to the brain shell. This theory is supported by the loss of sense of sense of sense or sleep, sleep disorders and constipation, the symptoms of the disease, such as chills and slowing the movement of motor symptoms start years ago. For this reason, in recent years, researchers have been searching for ways to stop the progression of the disease by identifying these non-motor symptoms as early as possible.